Mexican footballer Mario Ayala began his club career with América, reaching the First Division with the team in 1964. The same year Ayala was part of the Mexican squad that competed at the 1964 Tokyo Olympics, although he did not play in any matches. He continued to play for América, winning the Mexico Cup in 1965 and the First Division title the following year. In 1969 Ayala transferred to León where he spent the rest of his playing career. León finished as runners-up in the league in both the 1972/73 and 1974/75 seasons, and won the Mexico Cup in 1972 and 1975. Ayala played with the club until 1978 before returning to coach the team in the 1990s and early 2000s.