Enzo Frisoni joined the Juvenes Sports Society in San Marino in 1962, where he became a keen cyclist. Over the next few years Frisoni had a number of victories in the micronation and the surrounding areas of Italy. He represented San Marino at multiple international events including the 1966 UCI Road World Championships in Nürburgring, along with two editions of the Games of the Small States of Europe. In 1968 he was part San Marino’s four-man delegation to the Mexico City Olympics, finishing 61st in the road race.