Andrey Makeyev’s entire basketball career was spent in Leningrad/St. Petersburg and he was a member of the Spartak team that won the Soviet Union Championship in 1975. Makeyev was also runner-up in the Championship with Spartak on six occasions, and third twice. He also won the USSR Cup, and was twice winner of the European Cup Winners’ Cup. At the 1976 Olympics, Makeyev scored 10 points in four matches.
After the end of his playing career, Makeyev worked as a coach. In the 2000s he coached the women’s club Baltic Star. He later coached the St. Petersburg wheelchair team BasKI, and repeated his playing success by helping them become Russian champions. Makeyev also coached the Russian national wheelchair basketball team.